Exosomes Derived from Pancreatic Cancer Cells Induce Osteoclast Differentiation Through the miR125a-5p/TNFRSF1B Pathway
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چکیده
منابع مشابه
Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation
Bone disease is the most frequent complication in multiple myeloma (MM) resulting in osteolytic lesions, bone pain, hypercalcemia and renal failure. In MM bone disease the perfect balance between bone-resorbing osteoclasts (OCs) and bone-forming osteoblasts (OBs) activity is lost in favour of OCs, thus resulting in skeletal disorders. Since exosomes have been described for their functional role...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2021
ISSN: 1178-6930
DOI: 10.2147/ott.s282319